Elevate your expectations with Zebra's advanced healthcare desktop printers

You need a reliable printer built for healthcare that delivers quality performance, now and for years to come. It needs key features, and be easy to setup, operate, manage and maintain-onsite or remotely. It needs to be secure to protect patient information, whether integrated onto your network or not, to prevent downtime and costly cyberattacks. You need it, and Zebra delivers it, for more than 50 years. We've engineered our healthcare printers to match your workflows for hassle-free performance. Building on the legacy of Zebra's GK Series and ZD420 healthcare printers, the ZD421 delivers the flexibility and reliability you need, with even more capabilities and security, to set you up for years of use.

It's Time to Advance

Migrate from G to Z

The ZD421 builds on the legacy of Zebra's GK Series and ZD420 Series printers, offering you the functions and capabilities of its predecessor-and much more. The next-generation ZD421 leverages this heritage to deliver advanced features for a new era of intelligence and forward flexibility, packaged in a ready-to-work healthcare model.

Advance Your Healthcare Workflows

Easy to Clean, Sanitize and Safely Power

Disinfectant-ready plastics, UV-resistant housing and a sealed-button interface make the ZD421 healthcare printer easy to clean and sanitize, helping prevent the spread of infections in hospitals and clinics. And, the power supply is IEC 60601-1 compliant for use in healthcare facilities.

Simple to Use

Intuitive and Powerful Operation

The ZD421 offers new, advanced features that make it stand apart.It includes a new, more intuitive user interface, powerful architecture and field-upgradeable wireless kit. It also has new media guide and media handling designs that make daily operation even easier.

Supports Nearly Every Use Case

Multiple Models to Match Your Needs

Available in direct thermal, thermal transfer and ribbon cartridge models, all specifically for healthcare, the ZD421 healthcare printer meets a wide variety of healthcare-specific use cases and requirements.

• Print methods: Thermal Transfer or Direct Thermal
• ZPL and EPL programming languages
• 5 status icon, 3 button user interface
• USB 2.0, USB Host
• Printer setup mobile app for Android & iOS via BLE (Bluetooth Low Energy 5) connection
• Real Time Clock (RTC)
• Dual-wall frame construction
• ENERGY STAR® certified
• PDF Direct
• Two-year standard warranty